A. Can the Patient be Managed Safely at Home? - Is provider familiar with patient?
1. Good response (mild exacerbation) includes:
2. Incomplete response (moderate exacerbation) includes:
C. Has the Plan Worked? - Assess severity: measure PEF.
1. Severe: PEF < 50 percent personal best or predicted suggests severe exacerbation requiring medical attention
2. Partial: PEF > 50 percent < 70 percent of personal best or predicted
3. Good: PEF >70 percent of personal best or predicted
Note signs and symptoms: degree of cough, breathlessness, wheeze, and
chest tightness, correlates imperfectly with severity of exacerbation.
(Difficult for patient to self-assess).
| Intervention | References | Grade of Evidence | Strength of Recommendation |
| Symptoms (in severe +/-) are poor predictors of severity in severe asthma. | NAEPP, Expert Panel Report 2 1997
Grampian 1994 Charlton et al. 1994 |
B | 1 |
| Auscultated wheezes are poor predictors of severity. | Kikuchi et al. 1994
Holleman et al. 1995 |
C | 2a |
| Physician's impressions are inaccurate predictors of severity. | Kerem et al. 1991
Dales et al. 1988 Pratter et al. 1983 |
C | 2a |
| Intervention | References | Grade of Evidence | Strength of Recommendation |
| PEF meters and self-management plans are effective in improving control of severe and moderately severe asthma. | NAEPP, Expert Panel Report 2 1997
Hargreave et al. 1990 Woolcock et al. 1988 Ignacio-Gracia et al. 1995 Lahdensno et al. 1996 Beasley et al. 1989 Malo et al. 1993 |
B | 1 |
| Correlation with FEV1. | Malo et al. 1993 | A | 2a |
D. Instruct Patient to Come to Office or Emergency Room to be Seen Immediately - Poor response (severe exacerbation) includes:
1. PEF < 50 percent personal best or predicted
2. Marked wheezing and shortness of breath
3. Repeat beta2-agonist immediately, call doctor or proceed to emergency department; consider calling ambulance or 911.
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