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Table OP2.5    Opioids:  Dosage Formulations
OPIOIDS† ROUTE FORMULATIONS
PURE AGONISTS
Phenanthrenes    
Codeine PO Tablets/Capsules (doses in mg):
   Codeine alone 15, 30, 60
   Codeine/APAP 15/300, 30/300, 60/300
   Codeine/ASA 30/325, 60/325

Liquids:
  Codeine alone 15 mg/5 ml
   Codeine/APAP 12/120 mg/5 ml
IM
IV
SC
Injection:  30 and 60 mg/ml
Hydrocodone
 PO

Tablets/Capsules (doses in mg):
   Hydrocodone/APAP 2.5/500, 5/500, 7.5/650, 7.5/750, 10/325, 10/500,
   10/650
   Hydrocodone/ASA 5/500
   Hydrocodone/Ibuprofen 7.5/200

Liquid:
   Hydrocodone/APAP 2.5/167 mg/5 ml (7.5/500 mg/15 ml)
Hydromorphone PO Tablets:  1, 2, 3, 4 and 8 mg
Liquids:  5 mg/5 ml
IM
IV
SC
IV PCA		 Injection:  1, 2, 4, and 10 mg/ml
PR Suppositories:  3 mg
ED
IT 		Check label for preservative-free formulation for injection.
Levorphanol PO Tablets:  2 mg
IM
IV
SC		 Injection:  2 mg/ml
Morphine PO IR tablets:  15, 30 mg
CR/SR tablets:  15, 30, 60, 100, 200 mg
Liquids: 10 mg/5 ml, 20 mg/5 ml, 20 mg/1 ml
IM
IV
SC
IV PCA		 Injection:  0.5, 1, 2, 4, 5, 8, 10, 15, 25, 50 mg/ml


PCA syringes:  1 and 5 mg/ml, 30 ml
PR Rectal suppositories:  5, 10, 20, 30 mg
ED
IT 		Preservative-free injection:  0.5, 1, 10, 15, 25, and 50 mg/ml
Oxycodone PO IR tablets/capsules (doses in mg):
   Oxycodone alone 5, 15, 30
   Oxycodone/APAP:  2.5/325, 5/325, 5/500, 7.5/500, 10/650
   Oxycodone/ASA:  2.25/325, 4.5/325
   
CR tablets:  10, 20, 40 and 80 mg

Liquids:  
   Oxycodone alone 5 mg/5 ml, 20 mg/1 ml
   Oxycodone/APAP 5/325 mg per 5 ml
Oxymorphone IM
IV
SC 		Injection:  1 and 1.5 mg/ml
PR Suppositories:  5 mg
Phenylpiperidines   
Alfentanil ED Preservative-free Injection:  500 mcg/ml
Fentanyl IM
IV
IV PCA		 Injection:  50 mcg/ml
ED
IT 		Check label for preservative-free formulation for injection.
Meperidine PO Tablets:  50, 100 mg
Liquid:  50 mg/5 ml
IM
IV
SC
IV PCA		 Injection:  10, 25, 50, 75 & 100 mg/ml
ED Check label for preservative-free formulation for injection.
Remifentanil IV Preservative-free injection:  1 mg/ml
Sufentanil IV
IV PCA		 Injection:  50 mcg/ml
ED Preservative-free injection:  50 mcg/ml
Diphenylheptanes    
Methadone PO Tablets:  5 & 10mg
Liquids:  5 mg/5ml, 10 mg/5ml, 10 mg/1ml
IM
IV
SC 		Injection:  10 mg/ml
ED Check label for preservative-free formulation for injection.
Propoxyphene PO Tablets/capsules (doses in mg):
    Propoxyphene 65, 100
    Propoxyphene HCl/APAP 65/650
    Propoxyphene Napsylate/APAP 50/325, 100/650
    Propoxyphene HCl/ASA/Caffeine 65/389/32.4
MIXED AGONIST-ANTAGONISTS OPIOIDS
Buprenorphine IM
IV 		Injection:  0.324 mg (equivalent to 0.3 mg buprenorphine) / ml
Butorphanol IM
IV 		Injection:  1 and 2 mg/ml
Dezocine IM
IV
SC 		Injection:  5, 10, and 15 mg/ml
Nalbuphine IM
IV
SC 		Injection:  10 and 20 mg/ml
Pentazocine PO Tablets (doses in mg):
   Pentazocine/APAP 25/650
   Pentazocine/ASA 12.5/325
   Pentazocine/Naloxone 50/0.5
IM
IV
SC 		Injection:  30 mg/ml
Other    
Tramadol
 PO Tablets:  50 mg

†   Agents shown in bold are listed on the VA National Formulary (VANF, as of Dec. 2001); agents shown in italic are listed on the DoD Basic Core  Formulary (BCF, as of 15 Nov. 2001); agents shown in bold italic are listed on both the VANF and BCF. Check listings for specific formulations and  restrictions. 

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